Glossary

  • Ampoule
    Self-sealed container made of tubular glass in three standardized ISO types (B, C and D). In the case of pharmaceutical ampoules, a distinction is made between various systems for breaking open the ampoule: for example the One Point Cut, the Color Break and the Score Ring method.
  • Autoinjector
    An autoinjector is a medical device designed to deliver a single dose of a particular liquid drug. It facilitates self-administration by patients.
  • Backstop
    As a smart addition to its syringe range, Gerresheimer offers a Backstop. This system component is made of plastic and is machine-clipped to the existing finger flange of the glass syringe, thereby reducing its aperture diameter and preventing the plunger head from being pulled out of the syringe. At the same time the ergonomically shaped wings enlarge the finger flange to facilitate the application.
  • Baked-on RTF®
    ‘Baked-On RTF optimizes RTF® syringes for sensitive biotech medicines. This Gerresheimer process is patented in Europe and the USA. It consists of baked-on siliconization which fixes the silicone oil to the glass surface permanently and almost completely.
  • Biopharmaceuticals
    Biopharmaceuticals are substances produced by means of biotechnology in genetically modified organisms. Biopharmaceutics is one of the fastest growing product categories in the pharma and biotechnology industry.
  • Borosilicate Glass (Typ-I-Borosilicate Glass Tubing)
    Glass tubing made of the high-quality type I borosilicate glass which because of its chemical composition possesses the highest possible hydrolytic resistance and because of its low alkali emission is used particularly for injection substances.
  • Bulk syringes
    The term bulk syringes is used to describe syringe barrels supplied to the customer in an unsterilized state with or without a premounted needle. Washing, sterilization and mounting of the closure cap/needle shield before filling is carried out by the pharma company.
  • Clearject™ (COP-Syringe)
    Brand name of our Japanese partner Taisei Kako Co. Ltd. for sterile prefillable plastic syringes made of crystal-clear COP (Cyclic Olefin Polymer). These are particularly suitable for use in the demanding field of cytostatics and biopharmaceutics.
  • COP-Syringe (Clearject™)
    Brand name of our Japanese partner Taisei Kako Co. Ltd. for sterile prefillable plastic syringes made of crystal-clear COP (Cyclic Olefin Polymer). These are particularly suitable for use in the demanding field of cytostatics and biopharmaceutics.
  • Camera inspection systems
    During and after production the quality of Gerresheimer products is monitored by means of in-process controls. Modern optical camera systems and mechanical examination systems supported by special computer technology and digital image processing help to detect trends and variances and pick out defective articles at an early stage.
  • Cartridge
    The cartridge is a cylinder made of tubular glass which is closed at the front end by an aluminum cap with a membrane which is penetrated by the injection needle to draw in the injection solution.
  • Child resistant closure
    A child resistant closure protects children’s health by making pharmaceutical packaging difficult for them to open. Certain actions are necessary to open a child resistant closure that children find impossible to perform (without instruction). These are generally unusual opening actions, such as a combination of sequenced or simultaneous movements (e.g. press and turn caps).
  • Clean room
    In a clean room, special processes and equipment types control particle contamination. This is a key requirement for production of a wide range of drug delivery systems, primary packaging and certain pharmaceutical production processes.
  • Cytostatics
    Cytostatics are natural or synthetic substances which inhibit cell growth or division. They are used particularly in cancer treatment (chemotherapy) and sometimes also in the treatment of autoimmune disease.
  • Diabetes Care
    Medical specialism covering diabetes diagnosis and therapy. In this business field, Gerresheimer concentrates on development and production of highly innovative lancets, skin-prick aids and insulin pen systems.
  • Diagnostic Systems
    Systems for the analysis of organic liquids and materials outside the body (in vitro). In such systems, patient samples can be examined for specific parameters on a fully automated basis in many cases.
  • Drug Delivery Systems
    A drug delivery system transports the active substance in various ways (via pulmonary or nasal inhalation, through the skin, via the mucous membranes or orally) precisely to those areas in the body where it is intended to be effective. Examples: inhalers for the treatment of respiratory disease and prefillable syringes for injection drugs.
  • Disposable syringe systems (Prefillable syringe systems)
    Syringe systems, for example, Gerresheimer RTF® syringes, supplied to customers in the pharma and biotech industry for filling with prepared medications.
  • Dropper bottle system
    Special bottle system made of glass or plastic for delivery of medications in drop form, consisting of bottle, dropper and closure.
  • Heat Transfer Printing
    Heat transfer printing allows multicolor elements to be applied to glass syringes and cartridges in a single efficient process. Product information, calibrations and barcodes distinguished by different colors help to avoid confusion and application errors.
  • Hydrolytic resistance
    Criterion for the resistance of glass containers. Defined in terms of resistance against leaching of alkaline glass components through ultra-pure water.
  • Inhaler
    An inhaler is a device used in the treatment of asthma, bronchitis and other chronic respiratory ailments. It transports aerosol and powder-based medications into the upper and lower respiratory tracts.
  • Injection Vials (Vials)
    Vials are small-volume primary packaging containers made of tubular glass. In Gerresheimer the filling volume of vials for pharmaceutical applications ranges from 1 to 50 ml. These vials are often also referred to as injection vials as the fluid to be injected is drawn up from the vial by means of an injection needle.
  • Insulin Pen System
    An insulin pen is a special injection system for safe and less painful delivery of insulin from a cartridge.
  • Integrated moisture absorber
    A moisture absorber protects the pharmaceutical against the effects of moisture during storage and absorbs atmospheric humidity which enters the container as a result of it being repeatedly opened. Gerresheimer integrates the desiccant in a capsule affixed to the inside of the Duma® Twist-Off cap. 
  • Lancet
    A lancet is a blood-sampling needle which is extrusion-coated with plastic. It is inserted into a skin-prick aid for diabetic patients.
  • Lancet Magazine
    Magazine with integrated lancets in a drum housing.
  • Laser Coding
    With the new method of laser coding for syringes, a tiny data matrix code containing individual data about the nature and origin of the respective glass packaging is indelibly applied by laser to the finger flange. Gerresheimer thereby offers an innovative track-and-trace solution for pharma containers and also contributes to combating the problem of drug counterfeiting.
  • Life Science
    Life science is the field in which research institutes work primarily on the application of scientific findings in modern biology, chemistry and medicine as well as related areas, with a highly interdisciplinary and also market-based orientation.
  • Molecular diagnostics
    Molecular diagnostics refers to analysis methods based on examination of the genetic substance (DNA or RNA). These allow more precise information to be obtained than with traditional diagnostic procedures so that illnesses can be detected faster.
  • Moulded Glass
    Moulded glass packaging is produced in a single continuous work process directly after the melting process.
  • Multifunctional closure system
    The Gerresheimer closure systems comprise resistant and air-tight opening and closure devices which meet diverse requirements. All caps conform to ISO standards and can be combined with our glass and plastic packaging containers for liquids and solids. The multifunctional closures are tamper evident, child resistant, senior citizen friendly and moisture absorbing.
  • MultiShell® plastic vials
    These pharmaceutical primary packaging vials are made from COP plastic and PA (polyamide). COP stands for Cyclic Olefin Polymer, a glass-clear, breakresistant and biocompatible plastic type which is particularly suitable for long-term storage of sensitive parenteral medicines. With the new multilayer development combining two COP outer layers with a middle layer of polyamide, Gerresheimer has substantially enhanced the barrier properties against gas permeation to several times that of vials consisting of COP alone.
  • Needle Trap
    Label with integrated needle shield to avoid needle-prick injuries from syringes.
  • Ophthalmology
    The specialist medical field of ophthalmology (study of the eye) also covers diseases and malfunctions of the optical organ and the sense of sight and their medical treatment.
  • Paste Mould Technology
    Glass forming process using a rotation mould (blowing process) to form a round and seamless piece of glassware.
  • PharmaPlus
    Gerresheimer description for a whole range of high-caliber technical solutions in the forming of glass pharma containers, achieving a previously unattained level of precision. This includes the production of borosilicate tubes which Gerresheimer manufactures itself as intermediary products. The further refined equivalent for the forming processes has produced a new and outstanding quality category of tubular glass products whether they be syringes, cartridges, vials or ampoules.
  • Plastic Systems
    Complex and technically demanding systems consisting of several plastic components.
  • Primary packaging
    Packaging with which the filling contents come into direct contact.
  • Prefillable syringe systems (Disposable syringe systems)
    Syringe systems, for example, Gerresheimer RTF® syringes, supplied to customers in the pharma and biotech industry for filling with prepared medications.
  • RTF®-Spritzensysteme
    The leading Gerresheimer trademark RTF® stands for Ready to Fill. RTF® syringe systems are delivered to the customer washed, siliconized, assembled with the closure cap, packed in nests and tubs, and sterilized, in other words completely ready to fill. For the pharma manufacturer, this means that the whole chain of time-consuming process steps is avoided. The customer can therefore start filling the products straightaway. On high-speed production lines, this produces substantial cost and time advantages. Gerresheimers RTF® syringe portfolio is oriented towards modern pharma production.
  • Surface treatment
    Special finishing process on the inside of a pharmaceutical container, e.g. to ensure compatibility of the packaging material with the medication.
  • Siliconization
    Silicone oil is used as a glide agent in the inner surface treatment of pharmaceutical containers. This facilitates the action of the plunger inside the syringe barrel, which is essential for proper functioning of a syringe system.
    Baked-on RTF®
  • Skin-prick aid
    Device for diabetics by which a lancet can be inserted into the skin almost without pain. Some models permit different penetration depths to take account of the thickness of the skin.
  • Sterilized syringes
    Collective term for sterilized syringes supplied to the pharma industry completely ready to fill, for example, RTF® syringes.
  • Tamper evident closure
    A tamper evident closure is designed to signalize when a product is opened for the first time so that a patient will be aware if their medication has been tampered with. The Gerresheimer tamper-evident screw caps for tablet bottles (Duma® Twist-Off) have a ring on the cap which is detached from the cap by the twisting action when the container is opened for the first time. The pieces of plastic connecting the ring to the cap are torn off in the process, clearly indicating that the product has been opened. The tamper evident closures with Luerlock adapter for Gerresheimer syringe systems are activated by twisting. The tamper evident tabs on the twist-off closure (TELC) spread out as a result of the twist action to indicate that the syringe has been opened.
  • TCC
    Technical Competence Center. Here, products and systems are developed and brought to series readiness in collaboration with the customer.
  • TELC Tamper Evident Luerlock Closure
    The TELC is a Gerresheimer development for prefilled syringes and combines a tamper-evident closure and a Luerlock adapter.
  • TERNS - Rigid needle shield with thermoplastic elastomer
    TERNS is a closure developed by Gerresheimer for needle tips, with a soft sealing element made of thermoplastic elastomer (TPE) and a firm plastic shell.
  • TPE Thermoplastic elastomer
    Plastic which behaves like a classical elastomer at room temperatures, allows itself to be deformed when heat is added and therefore displays thermoplastic behavior.
  • Tubular Glass
    Tubular glass packaging is produced in two separate process steps: first of all production of the tubular glass and then forming.
  • Typ-I-Borosilicate Glass Tubing
    Glass tubing made of the high-quality type I borosilicate glass which because of its chemical composition possesses the highest possible hydrolytic resistance and because of its low alkali emission is used particularly for injection substances.
  • Vials (Injection Vials)
    Vials are small-volume primary packaging containers. These vials are often also referred to as injection vials as the fluid to be injected is drawn up from the vial by means of an injection needle.