Products & Solutions

Gx® Elite RTF Vials

Gx® Elite RTF Vials deliver pre-sterilized vials that simplify manufacturing, ensure drug integrity, enhance operational efficiency, and reduce total cost of ownership.

Enhanced Efficiency
Gx® Elite RTF Vials come pre-sterilized, removing the need for in-house washing and sterilization. This simplifies production processes, reduces downtime, and accelerates time-to-market

Improved Quality
The packaging design minimizes glass-to-glass and glass-to-metal contact, reducing particulate contamination and risks associated with vial damage or breakage. This ensures the integrity of both the packaging and the drug product

Flexibility in Operations
The EZ-fill® platform supports various configurations, including Nest & Tub and tray options, catering to both small and large production scales. It also integrates seamlessly with standard filling and finishing lines

Total Cost of Ownership (TCO) Reduction
By reducing operational steps and ensuring higher manufacturing efficiency, EZ-fill® helps lower the overall costs associated with drug production

Benefits of the Gx^® Elite RTF Vials

Internationally standardized product

De-risking of fill & finish

Reduced TCO

State-of-the-art production and inspection processes

Standardized packaging in nest & tub or tray

Sterilized with Ethylene Oxide gas

Gx® RTF configurations

Available formats / configurations

Packaging Type	Tub	Size “R”	Pieces Per Tray	Pieces Per Pallet
N+T	3"	2	100	18,000
N+T	3"	6	48	8,640
N+T	3"	10	48	8,640
N+T	3"	20	24	4,320
N+T	3"	30	24	4,320
N+T	3"	50	16	2,880
N+T	2"	2	120	36,000
N+T	2"	6	48	14,400
N+T	2"	10	48	14,400
N+T	2"	20	24	4,320
N+T	2"	30	24	4,320
Nested	N/A	2	228	45,600
Nested	N/A	6	96	19,200
Nested	N/A	10	96	19,200
Nested	N/A	20	60	9,600
Nested	N/A	30	60	7,200

Comparison Bulk vs. RTF Manufacturing

Bulk Line Processing

Complex Processing

Washing by WFI (70°C+)
Heat tunnel for sterilization (up to 350°C)
Additional failure modes
High efforts by quality

RTF Line Processing

Efficient Processing

Focus only on Fill & Finish process: no washing,
no heat tunnel
High-quality packaging directly entering filling line
Lower space requirements due to reduced footprint
Reduced number of operators to run the line

Take Advantage of our wide Range of Capabilities

Production sites in Europe, Americas and Asia for risk mitigation
Expansion coefficients 33 and 51
Inner siliconization for optimum emptying
Ammonium sulfate treatment to reduce alkali ion emission
Optimized design for lyophilization processes
Fully validated processes and certified suppliers according to cGMP
Ph. Eur., USP, JP, FEUM compliance
DMF type III

High-Technology Gx® G3 Vial Inspection

Proprietary visual inspection systems ensure cosmetic and dimensional quality.
Visual inspection of all areas of the vial: finish/neck, shoulder, body, hyper-bottom
Combination of 5 high resolution matrix and line-scan cameras
Proprietary lighting system
Custom software capable of defect recognition and classification
Bright and dark field images acquired at the same time help to characterize defects
Precision handling system for repeatability